Figure 3
Figure 3. Acute pulmonary toxicity in patient no. 1 associated with administration of CD8+ mHAg-specific CTLs. (A-B) Flow cytometric analysis of T-cell receptor expression in CTLs before infusion (A) and after recovery from bronchoalveolar lavage fluid (B) using a human TCR Vβ13-specific monoclonal antibody. (C-E) Chest radiographs taken before (C), 4 hours after (D), and 40 hours after (E) infusion of 2.25 × 109 CTLs.

Acute pulmonary toxicity in patient no. 1 associated with administration of CD8+ mHAg-specific CTLs. (A-B) Flow cytometric analysis of T-cell receptor expression in CTLs before infusion (A) and after recovery from bronchoalveolar lavage fluid (B) using a human TCR Vβ13-specific monoclonal antibody. (C-E) Chest radiographs taken before (C), 4 hours after (D), and 40 hours after (E) infusion of 2.25 × 109 CTLs.

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