A gallery of electron micrographs of platelets from patients with VWD2B. (A-B,E) Platelet agglutinates. (A) Membrane complexes (MCs) in an enlarged platelet. (D) Giant platelet from P1 with the P1266L mutation where high-molecular-weight (HMW) multimers are present despite a positive RIPA. (H) α-granule of increased size for P1. (G) Giant platelet from P6 with the V1316M mutation. (C,F) Enlarged platelets of abnormal form are shown for P7 (C) and for P4 (F). Many of the illustrated platelets contain increased amounts of surface-connected canalicular systems, and the granules are not homogeneously distributed. Scale bar equals 1 μm for all the electron micrographs.