Figure 3
Figure 3. Constitutively active c-Kit augments IL-33R signaling in BMMCs. (A) Surface expression of IL-33R and c-Kit in kitD814Vflox control (black dotted line) or kitD814V tg (black line) BMMCs. (B) kitD814Vflox control or kitD814V tg BMMCs were stimulated with IL-33 or SCF as indicated. Lysates were analyzed by immunoblot for phosphorylated signaling molecules as indicated.

Constitutively active c-Kit augments IL-33R signaling in BMMCs. (A) Surface expression of IL-33R and c-Kit in kitD814Vflox control (black dotted line) or kitD814V tg (black line) BMMCs. (B) kitD814Vflox control or kitD814V tg BMMCs were stimulated with IL-33 or SCF as indicated. Lysates were analyzed by immunoblot for phosphorylated signaling molecules as indicated.

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