Figure 1
DLEU7 at 13q14. (A) Schematic representation of minimal deleted region at 13q14 in CLL (adapted from Ouillette et al7 Fig 2 ). (B) Expression of DLEU7, miR-15a, and miR-16-1 in B-CLL samples. Relative expression levels of DLEU7, miR-15a, and miR-16-1 in 25 B-CLL samples, 4 lymphoid cell lines, and in normal CD19+ cells were assayed by real-time PCR. Expression levels of DLEU7, miR-15a, and miR-16-1 in CD19+ cells was set at 1. Expression levels of DLEU7, miR-15a, and miR-16-1 were normalized to the expression of GAPDH.
