Gas6 deficiency inhibits tumor growth in different tumor models. In all panels, the tumor size in Gas6^−/− mice is smaller than in WT mice. (A) Growth of orthotopic 4T1 breast tumors (n = 6-8; P < .05). (B) Growth of subcutaneous (s.c.) CT26 colon tumors (n = 7-9; P = .01). (C) Growth of subcutaneous Panc02 pancreatic tumors (n = 8-10; P = .02). (D) End-stage tumor volume of orthotopic Panc02 pancreatic tumors (n = 7-8; P = .01). (E) Growth of subcutaneous EL4 tumors (n = 6; P < .05). (F) End-stage tumor weight of subcutaneous EL4 tumors (n = 6; P = .001).