Detection of fibrin, TF, and C3 in glomeruli from mouse aPL antibodies (FB1, FC1, and FD1) and human aPL antibodies (aPL-IgG). (A) Fibrin staining in glomeruli from mice treated with FB1, FC1, FD1, and aPL-IgG antibodies after 1, 2, and 3 weeks of treatment. Mouse IgG and NH-IgG were used as control antibodies. (B) Immunohistochemical studies performed in kidneys from FB1-, FC1-, and aPL-IgG–treated mice showed increased TF expression. Increased C3 deposition was only observed in mice treated with FB1 and aPL-IgG.