Figure 3
Figure 3. Hyperproliferation of infected HSCs in the BM of HTLV-1-HU-NOD/SCID mice. (A) Predominance of CD34+/CD38− human stem cell subpopulation among human lymphocytes in the BM of the HTLV-1-HU-NOD/SCID mouse (iii) in comparison with mock-infected HU-NOD/SCID mouse (ii) when gated on human CD45 subpopulation (i). (B) Cumulative quantization of CD34+/CD38− and CD34+/CD38+ subpopulations in BM of HTLV-1 infected (n = 7) and mock-infected HU-NOD/SCID mice (n = 8).

Hyperproliferation of infected HSCs in the BM of HTLV-1-HU-NOD/SCID mice. (A) Predominance of CD34+/CD38 human stem cell subpopulation among human lymphocytes in the BM of the HTLV-1-HU-NOD/SCID mouse (iii) in comparison with mock-infected HU-NOD/SCID mouse (ii) when gated on human CD45 subpopulation (i). (B) Cumulative quantization of CD34+/CD38 and CD34+/CD38+ subpopulations in BM of HTLV-1 infected (n = 7) and mock-infected HU-NOD/SCID mice (n = 8).

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