Analysis of thymic function over time after BMT in all SCIDs. TREC values (N = 597) were observed over time in 115 patients for whom samples were available for analysis, each patient associated with 1 of 11 molecular types of SCID. (A) The combined results of all 115 patients. The points on the figure represent the predicted TREC value plus the residual after the patient and transplantation effects were removed. Lighter lines are then used to join points from the same patient before and 1 year after transplantation. The same analysis was performed for 15 IL7RαDef patients (B), 10 Jak3Def patients (C), and 57 γcDef patients (D); 95% confidence intervals were placed around the predicted TREC line over time for times more than 1 year after transplantation.