Normalization of splenomegaly of γc⁻ mice by transgenic expression of Cyclon. (A) Spleens from 8-week-old γc⁺, Cyclon-Tg γc⁺, γc⁻, and Cyclon-Tg γc⁻ mice. (B) Cell numbers of splenocytes, CD4⁺ splenic T cells, and CD8⁺ splenic T cells from γc⁺, Cyclon-Tg γc⁺, γc⁻, and Cyclon-Tg γc⁻ mice. (C) Expression of CD44 on CD4⁺ and CD8⁺ splenic T cells from γc⁺, Cyclon-Tg γc⁺, γc⁻, and Cyclon-Tg γc⁻ mice.