Table 1

Order of mutation sensitivity to dasatinib and nilotinib as determined by in vitro cell proliferation assays. Shading of O'Hare: red, resistant; yellow, intermediate sensitivity; and green, sensitive. Shading of Redaelli: red, highly resistant; orange, resistant; yellow, moderately resistant; and green, sensitive. Bold type indicates mutations where there is a difference in the classification between the studies. *Although T315A is rated as resistant, it is rarely detected.

Order of mutation sensitivity to dasatinib and nilotinib as determined by in vitro cell proliferation assays. Shading of O'Hare: red, resistant; yellow, intermediate sensitivity; and green, sensitive. Shading of Redaelli: red, highly resistant; orange, resistant; yellow, moderately resistant; and green, sensitive. Bold type indicates mutations where there is a difference in the classification between the studies. *Although T315A is rated as resistant, it is rarely detected.
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