Quantification of plasma cytokines after R-sIL-7gly injection. Plasma concentration of various cytokines (IL-1β, IL-1RA, IL-5, IL-10, IL-12, IL-13, IL-16, MCP-1, Eotaxin, granulocyte colony-stimulating factor, IFN-α, IFN-γ, CCL3, CCL4, CCL5, CCL-7, CCL27, CXCL8, CXCL9, MIF-3, nerve growth factor-β, stromal-derived factor-1, stem cell factor, tumor necrosis factor-related apoptosis-inducing ligand, and stem cell growth factor-β) was quantified over a week in animals receiving a single dose of R-sIL-7gly injection (no. 14424 and no. 14694, ■ and □, respectively) and in control animals using BioPlex assays. Control animals were no. 21045 and no 26007 not receiving IL-7gly (• and ○, respectively) and no. 17021 immunized against R-sIL-7 before R-sIL-7gly treatment (). This animal presented high levels of anti–IL-7–neutralizing antibodies. Only cytokines demonstrating significant variation are shown. (A) Cytokines implicated in LN homing. (B) Cytokines implicated in migration into nonlymphoid organs. (C) Molecules playing a role in transendothelial migration.