Overall survival by 3-year CR status. (A) For TT1, survival was superior in case complete response (CR) status had been sustained for 3 years (sus-CR), compared with not having attained CR (non-CR) and especially to having attained and lost CR (los-CR) within the 3-year time frame. (B) For TT2, survival was superior in case complete response (CR) status had been sustained for 3 years (sus-CR), compared with not having attained CR (non-CR) and especially to having attained and lost CR (los-CR) within the 3-year time frame. (C) For TT3, survival was superior in case complete response (CR) status had been sustained for 3 years (sus-CR), compared with not having attained CR (non-CR) and especially to having attained and lost CR (los-CR) within the 3-year time frame.