American Society of Hematology

Figure 4

MAPCs inhibit T-cell alloresponses through the secretion of PGE2. B6 > BALB/c MLR cultures were arranged as before. MAPCs, either untreated, treated overnight with 5 μM indomethacin to inhibit production of PGE2, or treated with vehicle, were titrated in at 1:10 ratios. Proliferation was assessed as above (panel A).

MAPCs inhibit T-cell alloresponses through the secretion of PGE₂. B6 > BALB/c MLR cultures were arranged as before. MAPCs, either untreated, treated overnight with 5 μM indomethacin to inhibit production of PGE₂, or treated with vehicle, were titrated in at 1:10 ratios. Proliferation was assessed as above (panel A).

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