KLRG1 modulates inflammatory cytokines produced by LPS-matured BMDCs. (A) CBA flex set for the anti-inflammatory cytokine mIL-10 was performed on supernatants from LPS-matured BMDCs incubated with or without the presence of KLRG1-expressing cells. The cytokines produced from these BMDCs in the presence of KLRG1 were then normalized to the cytokines produced from BMDCs in the presence of parental cells (parental cell average of 93 and 357 pg/mL for 6 and 12 hours, respectively). (B) CBA flex sets for the proinflammatory cytokines mTNF-α (parental cell average of 20 000 and 20 708 pg/mL for 6 and 12 hours, respectively) and mIL-6 (parental cell average of 19 874 and 25 834 pg/mL for 6 and 12 hours, respectively) were performed as described in panel A. The results are representative of at least 3 independent experiments (*, P < .05).