Diagrammatic representation of the differences of the means measured on the valvular versus the nonvalvular vein endothelium. (A) Diagram showing the locations of the endothelial confocal measurements made on the vein lumenal surface and in the valve sinus. (B-D) Graphic representations of the differences in mean intensity between the vein lumenal endothelium (combined areas A-C) and the valvular sinus endothelium (combined areas D-F) for EPCR, TM, and VWF, respectively. Paired t tests were used to test the differences in the means for each vein (see supplemental data and supplemental Table 1 with supporting data for this figure).