Kaplan-Meier survival curves according to RUNX1 mutation status. (A-B) A total of 330 AML patients receiving standard chemotherapy. (C-D) Those patients with normal karyotype. Data are shown for OS (A,C) and DFS (B,D). Tick marks represent patients whose data were censored at the last time they were known to be alive (A) or in CR (B) or at the time of HSCT.