The effect of down-regulation of RhoA and Rac1 on MM1s adhesion and chemotaxis. The effect of transient transfection of MM1s cells with siRNA on the expression of Rac1 (A) and RhoA (B) detected by immunoblotting and adhesion to fibronectin (C) and chemotaxis induced by SDF1. *P < .05; #P < .01.