cAMP inhibits cell death induced by DNA-damaging chemotherapeutic drugs. Reh cells were treated with or without forskolin or 8-CPT-cAMP for 30 minutes before addition of doxorubicin, daunorubicin, 4-OOH-CP, or cisplatin. Cells were then cultured for 18 hours before PI staining and FACS analysis (n = 4). *P < .01 compared with the corresponding samples treated with chemotherapeutics alone.