Expression of genes involved in MHC class I and II and angiogenesis and flow cytometric analysis of MCH class I and II molecules. Eisen tree map computed using the GeneSpring gene tree and the Pearson correlation equation on the modulated probe sets belonging to the categories of angiogenesis (A) and antigen presentation and processing via MHC class I and II (B). The signal-based coloring legend is shown at the bottom of the figure. Freshly separated normal and CML Lin⁻CD34⁺ and Lin⁻CD34⁻ cells were analyzed by flow cytometry for the expression of MHC class I and II molecules (C). The results are expressed as mean ± SD of 3 different experiments; *P < .05; MIF, mean intensity fluorescence.