Trans-SPECT images of monkeys with different CD4 T-cell counts. The total amount of injected DTPA-OKT4A/hIgG4 for each monkey was approximately 200 μg. (A) Time-activity curves of the radiotracer for the liver, kidneys, heart, and bladder at 1, 45, and 136 hours after radiotracer injection obtained from the whole-body images acquired in the uninfected RH4000 and the simian HIV_DH12R-infected RHCL6G. (B) Trans-SPECT total body image of the uninfected female CH3397. (C) Trans-SPECT sections of 4 monkeys. Spleen, tonsils, and axillary and inguinal lymph nodes regions of interest are circled. (D) Transversal sections of 4 monkeys. Right and left axillary lymph nodes are circled. The radioactivity in the middle is heart blood pool.