Percentage of expression of CD4^dimCD8^bright T cells is higher among LTNPs than among HIV seronegative donors. (A-B) Cumulative data (A) and representative dot plots (B) showing CD4 expression on CD8⁺ T cells obtained from 5 HIV⁻ and 8 HIV⁺ LTNP donors. (A) Horizontal lines represent the mean percentage of CD4^dimCD8^bright T cells within the CD8⁺ T-cell population. (C) Cumulative data showing TCRVβ clonotype expression of CD4⁻CD8⁺ and CD4^dimCD8^bright T cells from HIV⁺ LTNP and CMV⁺ donors. (D-E) Cumulative data showing TCR vβ clonotype expression of HIV⁺ LTNPs which are significantly increased (D) or decreased (E) between CD4⁻CD8⁺ and CD4^dimCD8^bright T cells. Closed squares denote CD4⁻CD8⁺ T cells and open circles denote CD4^dimCD8^bright T cells from HIV⁺ LTNP donors. P values between groups are indicated within the figure and based on 2-tailed unpaired t test analysis.