Comparisons of pairwise alignment scores and pairwise edit distances between M- and U-CLL mAbs. (A) Pairwise alignment scores. Pooled pairwise alignment scores for M-CLL peptides were significantly higher than those for U-CLL peptides (Student t test, P < .001). (B) Pairwise edit distances. As a group, M-CLL peptides had significantly shorter pairwise distances than did U-CLL peptides (Student t test, P < .001). The error bars extend to the extreme values of the data or 1.5× the height of the box, whichever is less. The height of the box represents the difference between the first and third quartiles. The top error bar in panel B merges with the top of the box plot for U-CLL peptides.