Figure 4
Heat maps of 13 diagnostic BCP-ALL samples, 1 relapse, and 2 cell lines. Focal deletions of CDKN2A/B, PAX5, and IKZF1. Data are divided by aberration: translocation, t(X;14)(p22;q32) and t(Y;14)(p11;q32), and deletion, del(X)(p22.33p22.33) and del(Y)(p11.32p11.32). For samples with the translocations (7 diagnostic, 1 relapse, and 2 cell lines), data were generated using the Human Genome CGH Microarray 244A platform and for samples with the deletion (6 diagnostic) the Human Genome CGH Microarray 105K platform was used. In all heat maps, each sample is represented by a single column, as indicated by the sample identifier at the head of the figure, and each row denotes the log2 ratio for each probe. The probes are plotted in genomic order (hg18) with losses and gains in blue and red, respectively. The size of the regions shown is given in parentheses. Note that the additional probes on the Human Genome CGH Microarray 105K platform for the PAR1 region failed.

Heat maps of 13 diagnostic BCP-ALL samples, 1 relapse, and 2 cell lines. Focal deletions of CDKN2A/B, PAX5, and IKZF1. Data are divided by aberration: translocation, t(X;14)(p22;q32) and t(Y;14)(p11;q32), and deletion, del(X)(p22.33p22.33) and del(Y)(p11.32p11.32). For samples with the translocations (7 diagnostic, 1 relapse, and 2 cell lines), data were generated using the Human Genome CGH Microarray 244A platform and for samples with the deletion (6 diagnostic) the Human Genome CGH Microarray 105K platform was used. In all heat maps, each sample is represented by a single column, as indicated by the sample identifier at the head of the figure, and each row denotes the log2 ratio for each probe. The probes are plotted in genomic order (hg18) with losses and gains in blue and red, respectively. The size of the regions shown is given in parentheses. Note that the additional probes on the Human Genome CGH Microarray 105K platform for the PAR1 region failed.

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