Figure 7
Figure 7. cANGPTL4 facilitates metastasis. (A-C) Representative macroscopic images of lungs (A); relative expression of melanin A (B); and representative eosin-stained images of lung sections (C). Black nodules in panel C indicate intravasated melanoma (n = 5). Micrographs of lung sections were taken with MIRAX MIDI (Carl Zeiss) with a Plan-Apochromatic 20×/0.8 objective and MIRAX Scan software. Scale bar: represents 100 μm. (D-E) Number of nodules (D) and weights of lungs (E) from wild-type and ANGPTL4-knockout C57BL/6J mice intravenously injected with either 5 × 105 B16F10CTRL or B16F10ΔANGPTL4 cells (n = 12). **P < .01; ***P < .001.

cANGPTL4 facilitates metastasis. (A-C) Representative macroscopic images of lungs (A); relative expression of melanin A (B); and representative eosin-stained images of lung sections (C). Black nodules in panel C indicate intravasated melanoma (n = 5). Micrographs of lung sections were taken with MIRAX MIDI (Carl Zeiss) with a Plan-Apochromatic 20×/0.8 objective and MIRAX Scan software. Scale bar: represents 100 μm. (D-E) Number of nodules (D) and weights of lungs (E) from wild-type and ANGPTL4-knockout C57BL/6J mice intravenously injected with either 5 × 105 B16F10CTRL or B16F10ΔANGPTL4 cells (n = 12). **P < .01; ***P < .001.

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