Figure 2
Figure 2. Unsupervised hierarchical clustering analysis of gene differentially expressed among CD34+ cells mobilized plerixafor, G-CSF, and plerixafor plus G-CSF in 3 rhesus macaques. The CD34+ cells were analyzed by gene expression profiling using a cDNA microarray with more than 17 000 genes. Among 5378 genes that were expressed in at least 80% of the samples and were increased at least 2-fold, 1097 were found to be differentially expressed in 3 clusters of CD34+ cells (F test, P ≤ .005). The differentially expressed genes were analyzed by hierarchical cluster of Eisen. G indicates G-CSF; A, plerixafor; A+G, plerixafor plus G-CSF.

Unsupervised hierarchical clustering analysis of gene differentially expressed among CD34+ cells mobilized plerixafor, G-CSF, and plerixafor plus G-CSF in 3 rhesus macaques. The CD34+ cells were analyzed by gene expression profiling using a cDNA microarray with more than 17 000 genes. Among 5378 genes that were expressed in at least 80% of the samples and were increased at least 2-fold, 1097 were found to be differentially expressed in 3 clusters of CD34+ cells (F test, P ≤ .005). The differentially expressed genes were analyzed by hierarchical cluster of Eisen. G indicates G-CSF; A, plerixafor; A+G, plerixafor plus G-CSF.

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