Phenotypic data for patients and family members. (A) Table showing laboratory results. Reference values are given for each assay. Ratios of antigen to activity are shown alongside activity columns. VWF indicates von Willebrand factor; Ag, antigen; RCo, ristocetin cofactor activity; CB, collagen-binding activity; and WT, wild type. Bleeding scores were calculated using the condensed MCMDM-1VWD questionnaire. (B) Gels showing VWF multimer pattern from plasma samples. Gray bars are placed to maintain patient confidentiality. Patient ID or type of control is shown at the bottom of each lane. A sample from 3J was not available for electrophoresis.