This figure shows the correlation between ITD insertion site, length, as well as the relative position of the Y591-Y599 motif of the 282 ITDs, sorted by insertion site. The light gray color symbolizes the duplicated fragment and the black color demonstrates the involvement of the amino acid motif Y591-Y599. The presence of additional material is depicted in darker gray. The majority of the 282 ITDs included at least a part of the specific amino acid stretch Y591-599. ITD indicates internal tandem duplication.