Prevalence of high TRV on Doppler echocardiography in the thalassemia cohort by age. Specific prevalence of a TRV ≥ 2.5 m/s for each age group is demonstrated, with the actual number of patients with a TRV ≥ 2.5 m/s listed above each age category. The greatest prevalence of TRV elevation occurs in the 41- to 50-year age group of the TCRN cohort.