Figure 2
Figure 2. TMPro expression results in a large metastatic burden even after injection of a relatively low tumor cell burden. Gross appearance of lung lobes harvested from WT (A) and TMPro mice (B) 13 days after intravenous injection of 3 × 104 LLCGFP cells. (C) This modest tumor cell inoculum resulted in essentially no pulmonary metastases in WT mice, whereas TMPro mice developed hundreds of metastatic foci. Horizontal bars represent medians.

TMPro expression results in a large metastatic burden even after injection of a relatively low tumor cell burden. Gross appearance of lung lobes harvested from WT (A) and TMPro mice (B) 13 days after intravenous injection of 3 × 104 LLCGFP cells. (C) This modest tumor cell inoculum resulted in essentially no pulmonary metastases in WT mice, whereas TMPro mice developed hundreds of metastatic foci. Horizontal bars represent medians.

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