Kinetics of differential DC gene expression induced by HIV-1 uptake and infection. Numbers of differentially expressed genes in response to viable and AT-2–treated HIV-1 are shown. Viable and AT-2–inactivated HIV-1–treated MDDC differentially expressed gene lists were generated after filtering according to B value. (A) Commonly expressed genes in viable and AT-2–inactivated HIV-1–treated MDDCs. The numbers of genes differentially expressed in response to viable and AT-2–inactivated HIV-1 at 6, 24, and 48 hours after treatment are illustrated by the solid and broken lines, respectively. The open histogram shows the numbers of genes differentially expressed in response to viable HIV-1 only, and the shaded area shows the number of genes that were commonly changed in their expression in cells treated with viable virus and those treated with AT-2–inactivated virus. (B) Commonly expressed genes between time points. The numbers of genes differentially expressed in response to viable and AT-2–inactivated HIV-1 at 6, 24, and 48 hours after treatment are illustrated by the solid line. The numbers of specific genes expressed at each time point, or common between 2 time points, are shown by the domes, with the number of genes shown. The dotted line illustrates the numbers of genes differentially expressed at all 3 time points with the number shown in a box with a broken line.