Survival curves of patients with BCL2⁺/MYC⁺ lymphomas according to the timing of MYC⁺ rearrangement and treatment regimen. (A) Timing of MYC⁺ rearrangement: at diagnosis or at relapse. x-axis represents cumulative survival; y-axis, time (years). (B) Treatment regimen. ● represent long-term survivors; x-axis, cumulative survival; y-axis, time (years); Dx, diagnosis; R, rituximab; HD, high-dose chemotherapy with or without stem cell transplantation; and P, palliative.