mHAs on transfused leukoreduced HOD blood are crosspresented into MHC class I by recipient APCs. (A) Expansion of OT-I T cells in the spleen of recipient mice after transfusion with HOD whole blood or HOD LR blood, control mice were transfused with blood from FVB donors. (B) Representative flow cytometry plots. (C) CFSE dilution of OT-I T cells in response to transfusion of HOD blood. Data shown are representative of 3 separate experiments with similar results.