Modulation of IL-4Rα expression on naive and memory T cells by IFN-λ1. Naive and memory T cells were stimulated with anti-CD2/3/28 beads, in the presence or absence of IFN-λ1. At different time points, the cells were surface stained with anti–IL-4Rα (black line). The filled histograms show staining with isotype-matched controls. Data for day 2 are shown, along with expression in freshly isolated cells.