Figure 7
Figure 7. Protection from death in a lethal influenza challenge. (A) Mice (n = 8) were immunized on day 0 and day 14 with the influenza NP construct and with or without adjuvant, followed by electroporation using the CELLECTRA adaptive constant current device after each immunization. (B) IFNγ ELISpot responses were measured on day 21. (C) On day 42, mice were challenge intranasally with 10 LD50 A/PR/8/34, an H1N1 influenza strain. Mortality associated with influenza infection was tracked over the course of 14 days.

Protection from death in a lethal influenza challenge. (A) Mice (n = 8) were immunized on day 0 and day 14 with the influenza NP construct and with or without adjuvant, followed by electroporation using the CELLECTRA adaptive constant current device after each immunization. (B) IFNγ ELISpot responses were measured on day 21. (C) On day 42, mice were challenge intranasally with 10 LD50 A/PR/8/34, an H1N1 influenza strain. Mortality associated with influenza infection was tracked over the course of 14 days.

Close Modal

or Create an Account

Close Modal
Close Modal