Figure 5
Adoptive transfer of PD-1–deficient DC provides innate protection against LM infection. Rag-1KO hosts received PBS control or 6 × 106 purified sDCs or 107 purified NK cells from Rag-1KO or DKO mice, and then intravenously challenged with 105 CFU LM the same day. Mice were killed at day 3 after infection. Spleen (A) and liver (B) LM counts (CFU per gram tissue) were measured. *P < .05.
