Figure 5
Figure 5. Reduced numbers of Gr1low monocytes in CX3CR1-deficient mice under atherosclerotic condition and rescue by Bcl2 expression. Blood monocyte levels of irradiated apoe−/− recipients of wt (□) and cx3cr1gfp/gfp (■) BM cells, either transgenic (hBcl2 tg) or nontransgenic (non-tg) for hMRP8bcl2. (A) Summary of total monocytes, identify as CD115+ cells (R2 gated cells, Figure 1A), as a percentage of ngWBC (R1 gated cells, Figure 1A); n = 12. (B) Summary of Gr1low monocytes levels (R4 gated cells, Figure 1A) as a percentage of total CD115+ monocyte levels (R2 gated cells, Figure 1A); n = 12. *P < .01, **P < .05 (Student t test).

Reduced numbers of Gr1low monocytes in CX3CR1-deficient mice under atherosclerotic condition and rescue by Bcl2 expression. Blood monocyte levels of irradiated apoe−/− recipients of wt (□) and cx3cr1gfp/gfp (■) BM cells, either transgenic (hBcl2 tg) or nontransgenic (non-tg) for hMRP8bcl2. (A) Summary of total monocytes, identify as CD115+ cells (R2 gated cells, Figure 1A), as a percentage of ngWBC (R1 gated cells, Figure 1A); n = 12. (B) Summary of Gr1low monocytes levels (R4 gated cells, Figure 1A) as a percentage of total CD115+ monocyte levels (R2 gated cells, Figure 1A); n = 12. *P < .01, **P < .05 (Student t test).

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