Conduits branch from the capsule and trabeculae and radiate into the human axillary lymph node. Immunohistochemistry illustrated that collagen fibers expressing fibronectin branched from the outer capsule of the lymph node and integrated with the fibroreticular cell network in the lymph node (A). Similarly, trabeculae that were constructed of collagen fibers and expressed fibronectin radiated deep into the lymph node, branched, and merged with the conduit network (B). Data are representative of 4 independent experiments.