Variation in genome stability of CLL. Sample CLL334 has a stable genome with immunoglobulin recombinations at 2p11.2 and 14q32.33 as the only “lesions.” Raw geometric mean data (Geomean Ratio) are shown in light gray and segmenter output (Segment) in maroon. Sample CLL687 has a very unstable genome exhibiting multiple lesions in addition to the immunoglobulin recombinations described in sample CLL334.