Effects of RGDS and tirofiban on VWF binding to αIIbβ3 on human, and murine WT and mmHH platelets. Binding of FITC-labeled human VWF to ADP-stimulated human platelets (•), murine platelets (■), and mmHH platelets (▴) was measured in the presence of increasing concentrations of RGDS (A) or tirofiban (B). The data shown are the mean of 3 experiments.