Response rates to H pylori eradication. Solid boxes indicate the response rates and their dimensions are proportional to the weight of the study. Horizontal lines indicate 95% CIs. The dashed vertical line indicates the weighted mean response rate for all studies (56.5%). Of 11 studies with response rates in excess of 56.5%, 8 were from Japan; of 13 studies with response rates less than 56.5%, 6 were from Japan. One study from Gasbarrini et al (Italy)²  did not report the response rate and was excluded from the analysis of the pooled estimate.