Figure 1
![Figure 1. Globin gene expression in murine yolk sacs; wt and PCCA KO. (A) Proportional β-type ([(x)/(βH1 + ϵy + βAdult)] × 100), gray lines; and α-type globin gene expression ([x/(ζ + α)] × 100), black lines; adult or embryonic (solid or dashed lines, respectively), in wt embryos at times indicated. (B) Fold-globin gene expression in PCCA KO, relative to wt (set equal to 1) in E10.5 yolk sac. (C) Percent embryonic β-type globin gene expression, ([(βH1 + ϵY)/(βH1 + ϵY + βAdult)] × 100), in yolk sacs from E12.5 and E14.5 PCCA KO [dashed line, 74.3% (± 3.3%), n = 4, and 41.6% (± 12.6%), n = 6, respectively] compared with E12.5 and E14.5 wt [solid line, 77.0% (± 6.2%), n = 9, P = n.s., and 20.5% (± 3.0%), n = 6, P < .05, respectively].](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/113/25/10.1182_blood-2008-09-171728/4/zh89990937620001.jpeg?Expires=1724234100&Signature=d0kS-lyHVsu0M8NkH-bPux7yDtNKV3WITqJNAcqWCjohDEnWChYe5oazwrfXahmB1if7iT5EoPdOcBLm4DF02NyfGLbOKK~hrt9KZAjoFWU~XO~9xY-OQ2yLyrtIm-ZJlzcnCa4NUY-eo5ATZoIqmRZUjz-2yX0574mOCgAPKXmvqPNR3NWt6hajQ~R95Vob-gR7B7UxtYQziv8XcrsfE3tnalxlD5Ye5Fz4oRHb7zI4p53ABRHgLuOWvlZ7WSPsoyyMeVX0c0SzSDdHjAAAsdXyXSlvLDKLL8tcbx~9upX0XugfVfksORoqXrH628R3Dv5V1HmM9uPKAIxzb~Gouw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Globin gene expression in murine yolk sacs; wt and PCCA KO. (A) Proportional β-type ([(x)/(βH1 + ϵy + βAdult)] × 100), gray lines; and α-type globin gene expression ([x/(ζ + α)] × 100), black lines; adult or embryonic (solid or dashed lines, respectively), in wt embryos at times indicated. (B) Fold-globin gene expression in PCCA KO, relative to wt (set equal to 1) in E10.5 yolk sac. (C) Percent embryonic β-type globin gene expression, ([(βH1 + ϵY)/(βH1 + ϵY + βAdult)] × 100), in yolk sacs from E12.5 and E14.5 PCCA KO [dashed line, 74.3% (± 3.3%), n = 4, and 41.6% (± 12.6%), n = 6, respectively] compared with E12.5 and E14.5 wt [solid line, 77.0% (± 6.2%), n = 9, P = n.s., and 20.5% (± 3.0%), n = 6, P < .05, respectively].
