Cumulative incidence by age of development of MDS in cases with dyskeratosis congenita. (A) Cases reported in the literature through 2008, N = 8. (B) Cases enrolled in the NCI IBMFS DC cohort through 2007, N = 5. Data are the cumulative proportion experiencing each event as the cause of failure; shaded area is the 95% pointwise confidence envelope. Vertical lines indicate the age at which patients were censored with or without MDS.