No NET formation in neutrophils from newborn babies. Yost et al examine NET formation by scanning electron microscopy following stimulation of isolated neutrophils with bacterial lipopolysaccharide (LPS). LPS-stimulated neutrophils from an adult donor were found to generate extensive extracellular lattices (left panels). In contrast, NET formation could not be detected when control or LPS-stimulated neonatal neutrophils were examined (middle panels: term; right panels: preterm). The net result of this novel defect was shown to be impaired extracellular killing of bacteria. See the complete figure in the article beginning on page 6419.