Figure 5
Figure 5. Correlation between the levels of mBLats, the CTL responses against lytic antigens (IE and EA) in the blood, and shed virion in the saliva of an AIM patient (IM10) immediately following diagnosis. (A) Level over time of mBLats expressed as the log of the percentage of infected memory B cells. (B,C) Levels over time of CTL responses against IE and EA antigens, respectively, expressed as the log of the percentages of tetramer-binding cells in the total CD8+ T-cell population. Note the values for CTLLats are not shown because none was detected at any time point. (D) Level of virions shed into saliva expressed as the logs of the number of virions per milliliter of saliva sample. (E) As in panel D, but from 40 days after diagnosis until approximately one year later. (F) As in panel D, but for patient IM9. (G) As in panel E, but for patient IM9.

Correlation between the levels of mBLats, the CTL responses against lytic antigens (IE and EA) in the blood, and shed virion in the saliva of an AIM patient (IM10) immediately following diagnosis. (A) Level over time of mBLats expressed as the log of the percentage of infected memory B cells. (B,C) Levels over time of CTL responses against IE and EA antigens, respectively, expressed as the log of the percentages of tetramer-binding cells in the total CD8+ T-cell population. Note the values for CTLLats are not shown because none was detected at any time point. (D) Level of virions shed into saliva expressed as the logs of the number of virions per milliliter of saliva sample. (E) As in panel D, but from 40 days after diagnosis until approximately one year later. (F) As in panel D, but for patient IM9. (G) As in panel E, but for patient IM9.

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