Kaplan-Meier survival analysis of patients with diffuse large B-cell lymphoma defined by functional or structural subsets of TP53 mutations. (A) Overall survival of patients with missense TP53 mutations. (B) Overall survival of patients with TP53 mutations in direct DNA-contact codons. (C) Overall survival of patients with inactivating TP53 mutations defined by yeast functional assays. (D) Overall survival of patients with TP53 mutations in the conserved regions IV and V.