All 4 patterns of HSC differentiation are observed in the recipients of single CD45^midRho⁻EPCR⁺⁺ cells. (A-D) Examples of individual mice repopulated with freshly isolated cells where colored areas represent donor WBCs of GM (red), B-cell (blue), and T-cell (yellow) lineages as a percentage of all WBCs over time after transplant. Data are stacked such that the sum of each lineage contribution represents the percentage donor contribution to all WBCs. (E-H) The separate donor contributions to the individual GM (red), B-cell (blue), and T-cell (yellow) lineages shown as bars. The percentage donor contribution to the total WBCs is shown as a gray area behind the bars.