Overall survival in years for patients treated with R-CHOP according to IPI score and expression levels of HLA-DRB and/or MYC. Cutoff point levels are above and below the median for both genes. Adverse gene level for HLA-DR is for expression below the median, whereas adverse gene level for MYC is for expression above the median (A) All IPI groups (N = 116). (B) Low IPI group (scores 0-2, N = 72). (C) High IPI group (scores 3-5, N = 36). The combined number of cases in panels B and C are fewer than in panel A because of several cases with missing IPI information.