Figure 3
Figure 3. Resolvin E1 rapidly reduces leukocyte rolling in mouse cremaster muscle venules. (A) The rolling fraction (percentage of rolling cells in the total flux of passing leukocytes in each venule) in 10 venules from mouse no. 1 (■) and 5 venules from mouse no. 2 (●). The horizontal lines are the means of rolling fractions from 15 venules of mice 1 and 2 before (−15 to 0 minutes) and after (0-30 minutes) RvE1 injection. The shaded shapes indicate each venule from the mice. (B) Representative recordings of fluorescent leukocytes in venular trees before and after RvE1 injection. Arrows show rolling leukocytes. (C) The rolling fractions (means ± SEM) from 3 mice. N indicates the number of venules analyzed in each mouse. **P < .005.

Resolvin E1 rapidly reduces leukocyte rolling in mouse cremaster muscle venules. (A) The rolling fraction (percentage of rolling cells in the total flux of passing leukocytes in each venule) in 10 venules from mouse no. 1 (■) and 5 venules from mouse no. 2 (●). The horizontal lines are the means of rolling fractions from 15 venules of mice 1 and 2 before (−15 to 0 minutes) and after (0-30 minutes) RvE1 injection. The shaded shapes indicate each venule from the mice. (B) Representative recordings of fluorescent leukocytes in venular trees before and after RvE1 injection. Arrows show rolling leukocytes. (C) The rolling fractions (means ± SEM) from 3 mice. N indicates the number of venules analyzed in each mouse. **P < .005.

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