Array CGH detects cryptic alterations in MDS patients with normal cytogenetics. (A) Proportion of patients with abnormal cytogenetics as detected by conventional cytogenetics (left) and by aCGH (right). (B) Whole genome frequency distribution of chromosomal alterations in lower-risk patients (n = 44) as detected by aCGH and visualized by SeeGH. Lines to the right of the chromosome indicate gain of chromosomal material. Lines to the left of the chromosome indicate loss of chromosomal material.