Analysis of the competitive repopulating ability (CRA) of HSCs transduced with LVs as deduced from the analysis of primary to quaternary recipients. (A) CRA of HSCs exposed to LVs relative to the CRA of non–LV-exposed HSCs (percentage of Ly5.1 positive cells with respect to the whole population) in primary to quaternary recipients corresponding to experiment no. 2. (B) CRA of HSCs transduced with LVs relative to the CRA of HSCs exposed to, but not transduced with, the LVs (percentage of EGFP-positive cells inside Ly5.1⁺ population) in primary to quaternary recipients. ■ correspond to retransplantation data obtained from primary recipient B1, whereas △ correspond to retransplantation data from recipient F1.